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Peptides and Vitamin C: Can They Be Used Together?

In the world of skincare, there’s a wide range of active ingredients that promise impressive results. Two of the most popular ones are peptides and vitamin C, known for their anti-aging and brightening properties. But is it a good idea to mix peptides and vitamin C? In this article, we’ll explore the compatibility of these powerful ingredients and how to get the most out of them in your beauty routine.

2th of April 2025

By Biotherm

What are peptides and how do they work on the skin?

Peptides are short chains of amino acids, which are the building blocks of proteins. Proteins are essential for skin structure and function, including the production of collagen and elastin. As we age, natural collagen production decreases, leading to wrinkles, sagging and loss of elasticity.

This is where peptides come into play. When applied topically, they act as messengers that tell the skin to produce more collagen and elastin. This helps to fill wrinkles, improve firmness and elasticity and promote a more youthful appearance.

What is Vitamin C and how does it work on the skin?

Vitamin C is a powerful antioxidant that protects the skin from damage caused by free radicals, such as pollution and UV radiation. Free radicals can damage skin cells, leading to premature aging and the appearance of wrinkles and dark spots.

In addition to its antioxidant action, vitamin C is also essential for collagen production. It stimulates the synthesis of new collagen and helps protect existing collagen from breaking down. This means firmer, smoother and more radiant skin.

Can I mix peptides and vitamin C?

Good news! In general, peptides and vitamin C can be mixed. In fact, this combination can be very beneficial for the skin. Both ingredients work in synergy to promote collagen production, protect the skin from environmental damage and improve skin tone and texture.

However, it’s important to keep in mind that vitamin C is a relatively unstable ingredient that can easily oxidize, reducing its effectiveness. Therefore, it’s crucial to choose products that combine both ingredients in pH-stable formulations.

Other ingredient combinations with peptides

In addition to vitamin C, peptides can be combined with other ingredients to enhance their benefits. Here are some popular combinations:

Peptides and retinol

Retinol is another star ingredient in the anti-aging world. It stimulates cell renewal, improves skin texture and reduces the appearance of wrinkles and blemishes. The combination of peptides and retinol can be very effective in combating the signs of aging, but it should be introduced gradually into the skincare routine to avoid irritation.

Peptides and hyaluronic acid

Hyaluronic acid is a humectant that attracts and retains moisture in the skin, keeping it hydrated, soft and supple. The combination of peptides and hyaluronic acid is ideal for deeply hydrating the skin, filling wrinkles and improving elasticity.

Peptides and ferulic acid

Ferulic acid is an antioxidant that protects the skin from sun damage and enhances the action of other antioxidants such as vitamin C. The combination of peptides, vitamin C and ferulic acid is a triple threat against premature aging, the appearance of wrinkles and hyperpigmentation.

Biotherm products with Peptides

Biotherm offers a range of products formulated with peptides to help you achieve younger, firmer and more radiant skin. Here are some of them:

BLUE PEPTIDES UPLIFT SPF 30

This moisturizing day cream protects the skin from the sun thanks to its SPF 30, while its peptides help reduce the appearance of wrinkles and fine lines.

BLUE PEPTIDES UPLIFT DAY CREAM

Formulated with a high concentration of peptides, this day cream helps firm skin, improve elasticity and reduce the appearance of wrinkles.

BLUE PEPTIDES UPLIFT NIGHT CREAM

This nourishing night cream works while you sleep to promote cell regeneration, reduce wrinkles and improve skin firmness and elasticity.

BLUE PEPTIDES UPLIFT DAY CREAM FOR DRY SKIN

Specifically designed for dry skin, this day cream provides intense hydration, while peptides help fight the signs of aging.

Biotherm products with Vitamin C

Life Plankton Regenerating Serum

This iconic serum by Biotherm contains a high concentration of Biotech Plankton™, a unique ingredient that regenerates, soothes and protects the skin. Although it doesn’t contain vitamin C, its antioxidant and regenerating effects make it an ideal complement to an anti-aging skin care routine.

Biotherm products with Retinol or its derivatives

Blue Peptides Uplift Day Cream

This day cream doesn’t contain retinol as such, but it does include ingredients that promote cell renewal in a way similar to retinol — only gentler on the skin.

Blue Pro-Retinol Eye Cream

This eye contour cream is formulated with pro-retinol, a retinol precursor that converts to retinol upon contact with the skin. It helps reduce the appearance of wrinkles, fine lines and dark circles under the eyes.

In short, the combination of peptides and vitamin C can be very beneficial for the skin, as long as products have stable formulations and the right pH balance. If you’re looking for a complete anti-aging routine, we recommend incorporating products that combine both ingredients, such as those in Biotherm's Blue Peptides Uplift range.

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